Icons in eWay-CRM Online in desktop Outlook are not clickable. They are disabled.
All versions of eWay-CRM
Option 1: No selected email
The reason is that you don't have selected any email. Preview panes are bound to a selected email.
Option 2: Different view in Outlook
The issue is related to the way emails are displayed. You need to have emails displayed with their preview panel, not just list:
Go to View in Outlook and click Change View. Select Compact.
In this view, eWay-CRM Online is enabled.